Matthew Caines

I’m a patent attorney with a strong research background and extensive technical expertise. I enjoy applying this knowledge to make a real difference for my clients.

I joined D Young & Co in 2012 and work on a wide range of biotechnological and chemical subject matter. My practice includes the drafting and prosecution of applications, opposition and appeal proceedings, and freedom to operate opinion work. I’ve worked for a range of clients – from academic institutes and start-ups to multi-national companies.

Before joining D Young & Co, I obtained a DPhil from the University of Oxford where my research focused on the natural biosynthetic pathway of a clinically important antibiotic. I carried out postdoctoral research at the Medical Research Council Laboratory of Molecular Biology in Cambridge, where I investigated the immune response to HIV and influenza virus infections; and at the University of British Columbia, where I studied a number of enzymes linked to bacterial and viral pathogenesis. My research has been extensively published in peer-reviewed journals.

Publications

• Caines, M.E. et al. (2012) Diverse HIV viruses are targeted by a conformationally dynamic antiviral. Nat. Struct. Mol. Biol. 19: 411-416.
• Hancock, S.M. et al. (2009) Designer enzymes for glycosphingolipid synthesis by directed evolution. Nat. Chem. Biol. 5: 508-514.
• Caines, M.E. et al. (2008) The structural basis for T-antigen hydrolysis by Streptococcus pneumoniae, a potential target for structure-based vaccine design. J. Biol. Chem. 283: 31279-31283.
• Caines, M.E. et al. (2007) The structural basis of glycosidase inhibition by five-membered iminocyclitols. Angew. Chem., Int. Ed. 46: 4474-4476.