Rhys Pryce
I have a technical background in structural biology, biochemistry, and molecular biology; and a particular interest in virology, immunology, and protein engineering. I joined the biotechnology patents team at D Young & Co in 2020, having conducted DPhil and postdoctoral research in structural and molecular virology.
Since joining D Young & Co I have assisted with various aspects of patent prosecution and opposition, both in the UK and overseas. My work encompasses a variety of exciting and cutting edge technologies, principally within the life sciences.
Prior to joining D Young & Co I completed an undergraduate biochemistry degree, during which I undertook a year-long research placement at Monash University, Melbourne, investigating the molecular basis of lipid antigen recognition by T cells. I subsequently undertook DPhil and postdoctoral research within the Division of Structural Biology (STRUBI) at the University of Oxford, where I studied the interactions between emerging viruses and host factors, such as entry receptors and antibodies.
Qualifications
- BSc (Hons) Biochemistry with professional placement, University of Bath, 2014.
- Bill Whish Prize, University of Bath, best overall biochemistry degree performance.
- Robert Eisenthal Prize, University of Bath, best placement performance.
- DPhil Cellular Structural Biology, New College, University of Oxford, 2018.
- Certificate in Intellectual Property Law, Queen Mary, University of London.
Memberships
- Student member of the Chartered Institute of Patent Attorneys (CIPA).
- Student member of the European Patent Institute (epi).
Publications
- Moreno, H., Rastrojo, A., Pryce, R., et al., 2020. A novel circulating tamiami mammarenavirus shows potential for zoonotic spillover. PLOS Neglected Tropical Diseases 14(12): e0009004. https://doi.org/10.1371/journal.pntd.0009004
- Avanzato, V., A., Matson, M., J., Seifert, S., N., Pryce, R., et al., 2020. Case Study: Prolonged Infectious SARS-CoV-2 Shedding from an Asymptomatic Immunocompromised Individual with Cancer. Cell, Volume 183, Issue 7, 1901 – 1912.e9
- Pryce, R., et al. 2020. A key region of molecular specificity orchestrates unique ephrin-B1 utilization by Cedar virus. Life Sci Alliance. DOI: 10.26508/lsa.201900578
- Avanzato, V. A., Oguntuyo, K.Y., Escalera-Zamudio, M., Gutierrez, B., Golden, M., Pond, S. L. K., Pryce, R., et al. 2019. A structural basis for antibody-mediated neutralisation of Nipah virus reveals a site of vulnerability at the fusion glycoprotein apex. Proc. Natl. Acad. Sci. U.S.A. 116, 25057-25067.
- Pryce, R., et al. 2018. Structure-based classification defines the discrete conformational classes adopted by the arenaviral GP1. J Virol. DOI: 10.1128/JVI.01048-18.
- Lu, J., Raghwani, J., Pryce, R., et al. 2018. Molecular Evolution, Diversity, and Adaptation of Influenza A (H7N9) Viruses in China. Emerg Infect Dis, 24, 1795-1805.
- Chennamadhavuni, D., Saavedra-Avila, N. A., Carreno, L. J., Guberman-Pfeffer, M. J., Arora, P., Yongqing, T., Pryce, R., et al. 2018. Dual Modifications of alpha-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T cells and Stimulate Anti-tumor Immunity. Cell Chem Biol, 25, 925.
- Li, S., Sun, Z., Pryce, R., et al. 2016. Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike. PLoS Pathog, 12, e1005418.